• Longitudinal changes in concentrations of persistent organic pollutants (1986–2016) and their associations with type 2 diabetes mellitus 

      Charles, Dolley; Berg, Vivian; Nøst, Therese Haugdahl; Bergdahl, Ingvar A.; Huber, Sandra; Ayotte, Pierre; Wilsgaard, Tom; Averina, Maria; Sandanger, Torkjel M; Rylander, Charlotta (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-28)
      Background: Positive associations have been reported between persistent organic pollutants (POPs) and type 2 diabetes mellitus (T2DM); however, causality has not been established. Over the last decades, environmental exposure to legacy POPs has decreased, complicating epidemiological studies. In addition, physiological risk factors for T2DM may also influence POP concentrations, contributing to ...
    • Polybrominated diphenyl ethers in type 2 diabetes mellitus cases and controls: Repeated measurements prior to and after diagnosis 

      Charles, Dolley; Berg, Vivian; Nøst, Therese Haugdahl; Wilsgaard, Tom; Bergdahl, Ingvar A.; Huber, Sandra; Ayotte, Pierre; Averina, Maria; Sandanger, Torkjel M; Rylander, Karin Charlotta Maria (Journal article; Tidsskriftartikkel, 2023-03-05)
      <p><i>Background:</i> Previous studies have reported associations between certain persistent organic pollutants (POPs) and type 2 diabetes mellitus (T2DM). Polybrominated diphenyl ethers (PBDEs) are a class of POPs that are found in increasing concentrations in humans. Although obesity is a known risk factor for T2DM and PBDEs are fat-soluble, very few studies have investigated associations between ...
    • Pre- and post-diagnostic blood profiles of chlorinated persistent organic pollutants and metabolic markers in type 2 diabetes mellitus cases and controls; a pilot study 

      Berg, Vivian; Charles, Dolley; Bergdahl, Ingvar A.; Nøst, Therese Haugdahl; Sandanger, Torkjel M; Tornevi, Andreas; Huber, Sandra; Fuskevåg, Ole Martin; Rylander, Charlotta (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-09)
      Objective - Several risk factors for type 2 diabetes mellitus (T2DM) are also associated with blood concentrations of persistent organic pollutants (POPs), and factors related to the disease may affect POP concentrations, and subsequent associations between POPs and T2DM. The purpose of this pilot study was to investigate the change in concentrations of lipids, hormones and POPs pre- and post-diagnosis ...
    • Pre- and post-diagnostic blood profiles of perfluoroalkyl acids in type 2 diabetes mellitus cases and controls 

      Charles, Dolley; Berg, Vivian; Nøst, Therese Haugdahl; Huber, Sandra; Sandanger, Torkjel M; Rylander, Charlotta (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-09)
      <i>Background</i> - Studies exploring the associations between perfluoroalkyl acids (PFAAs) and type 2 diabetes mellitus (T2DM) are rather limited and have reported conflicting results. All studies to date, including prospective ones, have relied on a single blood sample to study this association. Similarly, studies investigating how T2DM status may influence the longitudinal changes in PFAA ...